Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845497 | 1.00 | AKR1B1 (0.40) | AKR1B1L3MBTL1FGFR4KMT2AMEN1 | |
| SCHEMBL4971376 | 0.88 | AKR1B1 (0.44) | AKR1B1L3MBTL1FGFR4KMT2AMEN1 | |
| SCHEMBL4971386 | 0.88 | AKR1B1 (0.44) | AKR1B1L3MBTL1FGFR4KMT2AMEN1 | |
| SCHEMBL9142159 | 0.83 | KMT2A (0.45) | AKR1B1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9142156 | 0.83 | KMT2A (0.45) | AKR1B1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16101298 | 0.83 | AKR1B1 (0.46) | AKR1B1L3MBTL1FGFR4KMT2AMEN1 | |
| SCHEMBL450748 | 0.81 | AKR1B1 (0.46) | AKR1B1L3MBTL1KMT2AMEN1GFER | |
| SCHEMBL9148051 | 0.77 | AKR1B1 (0.46) | AKR1B1L3MBTL1KMT2AMEN1GFER | |
| SCHEMBL9147726 | 0.77 | AKR1B1 (0.43) | AKR1B1L3MBTL1KMT2AMEN1GFER | |
| SCHEMBL446546 | 0.75 | MAPT (0.45) | AKR1B1ALDH1A1MAPTRAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432893-A2 | Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |