Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145972 | 0.94 | AGTR1 (0.81) | AGTR1 | |
| SCHEMBL9142149 | 0.91 | AGTR1 (0.90) | AGTR1 | |
| SCHEMBL9032504 | 0.89 | EDNRA (0.70) | AGTR1 | |
| SCHEMBL9141854 | 0.87 | AGTR1 (0.70) | AGTR1 | |
| L-159913 SCHEMBL9144158 | 0.85 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL9142724 | 0.84 | — | — | |
| SCHEMBL9565990 | 0.84 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL9144349 | 0.84 | AGTR1 (0.70) | AGTR1 | |
| SCHEMBL9142023 | 0.84 | AGTR1 (0.88) | AGTR1 | |
| SCHEMBL9146530 | 0.84 | EDNRA (0.72) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |