Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142943 | 0.92 | AGTR1 (0.74) | AGTR1 | |
| SCHEMBL9145114 | 0.90 | AGTR1 (0.78) | AGTR1AGTR2 | |
| SCHEMBL9374429 | 0.87 | AGTR1 (0.65) | AGTR1 | |
| SCHEMBL9377175 | 0.85 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL9142855 | 0.84 | AGTR1 (0.87) | AGTR1AGTR2 | |
| SCHEMBL12234367 | 0.84 | AGTR1 (0.76) | AGTR1 | |
| SCHEMBL9142491 | 0.83 | AGTR1 (0.66) | AGTR1 | |
| SCHEMBL9142041 | 0.82 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9399051 | 0.82 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9144279 | 0.82 | AGTR1 (0.78) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0586513-A1 | ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO. INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| US-5281614-A | Hypotensive agents, glaucoma or angiotensin antagonists | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0526001-A1 | Substituted triazolinones | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993001177-A1 | SUBSTITUTED TRIAZOLINONES | MERCK & CO., INC. (US) | 1993-01-21 | — | — | WO | disclosed |
| WO-1992020662-A1 | ACIDIC ARALKYL TRIAZOLE DERIVATIVES ACTIVE AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |