Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028466 | 0.98 | HTR2A (0.39) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| SCHEMBL9145143 | 0.96 | HTR2A (0.38) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| Methane SCHEMBL28813011 | 0.96 | HTR2A (0.38) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| SCHEMBL9145850 | 0.96 | HTR2A (0.38) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| SCHEMBL9145856 | 0.96 | HTR2A (0.38) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.96 | HTR2A (0.38) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| Ethyne SCHEMBL28884068 | 0.94 | HTR2A (0.36) | HTR2AHTR6SIGMAR1ATMEDNRA | |
| SCHEMBL15814999 | 0.86 | KDM1A (0.37) | HTR2AHTR6SIGMAR1TP53CYP3A4 | |
| Benzene SCHEMBL28734247 | 0.84 | HTR6 (0.51) | HTR2AHTR6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL2830664 | 0.83 | PRCP (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372954-B | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | disclosed |
| US-5391660-A | Narrow molecular weight distribution by addition polymerizing a olefin or mixtures in a catalysts mixtures having metal compounds, halometal compound and alumoxanes | NIPPON OIL COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |