Lithium

Lithium

SCHEMBL9145356

CC1=CC(C)c2ccccc21.[Li]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.37
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ATM Q13315 2/20 0.33
HTR2A P28223 1/20 0.32
POLB P06746 1/20 0.31
PKM P14618 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PBRM1 Q86U86 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
ACHE P22303 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356718 0.98 GPR3 (0.38) GPR3MEN1KMT2AATMHTR2A
SCHEMBL29385315 0.98 GPR3 (0.38) GPR3MEN1KMT2AATMHTR2A
SCHEMBL9145348 0.95 GPR3 (0.37) GPR3MEN1KMT2AATMHTR2A
SCHEMBL9146475 0.95 GPR3 (0.37) GPR3MEN1KMT2AATMHTR2A
SCHEMBL9146467 0.95 GPR3 (0.37) GPR3MEN1KMT2AATMHTR2A
SCHEMBL19117487 0.73 GPR3 (0.37) GPR3MEN1KMT2AHTR2APOLB
SCHEMBL8028884 0.73 GPR3 (0.37) GPR3MEN1KMT2AATMHTR2A
SCHEMBL4651597 0.73 GPR3 (0.41) GPR3MEN1KMT2AATMHTR2A
SCHEMBL10361233 0.73 GPR3 (0.37) GPR3MEN1KMT2AHTR2APOLB
SCHEMBL30544531 0.73 GPR3 (0.37) GPR3MEN1KMT2AHTR2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1930193-B Class of metallocenes and method of producing polyethylene UNIVATION TECH LLC 2011-03-23 CN disclosed
CN-1930193-A Class of metallocenes and method of producing polyethylene UNIVATION TECH LLC (US) 2007-03-14 CN disclosed
US-5391660-A Narrow molecular weight distribution by addition polymerizing a olefin or mixtures in a catalysts mixtures having metal compounds, halometal compound and alumoxanes NIPPON OIL COMPANY, LIMITED (JP) 1995-02-21 US disclosed