Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145411 | 1.00 | MEN1 (0.42) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258270 | 0.89 | MEN1 (0.43) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258272 | 0.89 | MEN1 (0.43) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258612 | 0.83 | MEN1 (0.46) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258617 | 0.83 | MEN1 (0.46) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL7841214 | 0.83 | NPSR1 (0.44) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL8696157 | 0.83 | NPSR1 (0.44) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL7432042 | 0.82 | MEN1 (0.59) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL7851531 | 0.82 | NPSR1 (0.43) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL9088978 | 0.82 | MEN1 (0.43) | MEN1KMT2ADHODHGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |