Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258270 | 1.00 | MEN1 (0.43) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL9145408 | 0.89 | MEN1 (0.42) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL9145411 | 0.89 | MEN1 (0.42) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL9537592 | 0.88 | DHODH (0.51) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258612 | 0.86 | MEN1 (0.46) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL7009560 | 0.86 | NPSR1 (0.41) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL5258617 | 0.86 | MEN1 (0.46) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL7009563 | 0.86 | NPSR1 (0.41) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL8131603 | 0.86 | NPSR1 (0.42) | MEN1KMT2ADHODHGAAKDM4E | |
| SCHEMBL9088978 | 0.85 | MEN1 (0.43) | MEN1KMT2ADHODHGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60228479-A | — | — | None | — | — | JP | disclosed |
| EP-1572657-B1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORP (KR) | 2007-07-11 | — | — | EP | disclosed |
| US-7220861-B2 | Processes for preparing quinolonecarboxylate derivatives | YUHAN CORPORATION (KR) | 2007-05-22 | — | — | US | disclosed |
| US-20060058528-A1 | Processes for preparing quinolone carboxylate derivatives | YUHAN CORPORATION (KR) | 2006-03-16 | — | — | US | disclosed |
| EP-1572657-A4 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORP (KR) | 2006-03-01 | — | — | EP | disclosed |
| EP-1572657-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | Yuhan Corporation (KR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056781-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORPORATION (KR) | 2004-07-08 | — | — | WO | disclosed |
| JP-S60228479-A | 1,4-DIHYDRO-4-OXONAPHTHYRIDINE DERIVATIVE AND SALT THEREOF | TOYAMA CHEM CO LTD | 1985-11-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058528-A1 | Processes for preparing quinolone carboxylate derivatives | QARS1, NQO2, QPCT | MEN1 2732/4885KMT2A 2553/4885DHODH 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.