Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148323 | 0.88 | EPHA2 (0.48) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6220162 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL31435135 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9416404 | 0.85 | EPHA2 (0.38) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL10512040 | 0.85 | EPHA2 (0.52) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9147090 | 0.83 | EPHA2 (0.53) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL9148818 | 0.83 | STAT3 (0.51) | ALDH1A1KDM4EKMT2ALMNAHTT | |
| SCHEMBL7008874 | 0.83 | TOP1 (0.51) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL6210375 | 0.82 | TOP1 (0.53) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 | |
| SCHEMBL13581395 | 0.82 | TOP1 (0.53) | ALDH1A1KDM4EPOLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | claimed |
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |