Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.56 |
| ▸ | PGR | P06401 | 10/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650258 | 0.94 | AR (0.57) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL15094157 | 0.94 | AR (0.67) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL3678661 | 0.94 | AR (0.67) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL10399827 | 0.94 | AR (0.67) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL4664713 | 0.94 | AR (0.67) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL9647584 | 0.92 | AR (0.62) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL14656547 | 0.91 | AR (0.57) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL14666086 | 0.91 | AR (0.57) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL20235298 | 0.91 | AR (0.57) | ARNR3C1PGRNR3C2ESR1 | |
| SCHEMBL9740103 | 0.91 | AR (0.57) | ARNR3C1PGRNR3C2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446036-A | Contraceptive | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | claimed |
| US-5089488-A | Anticarcinogenic agents; treating glaucoma, hypertension, diabetes, insomia, osteoporosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | claimed |
| EP-0254670-A1 | 11-beta-(4-isopropenylphenyl)-estra-4,9-diene, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-01-27 | — | — | EP | claimed |
| US-4814327-A | ANTIPROGESTERONE, ANTIGLUCOCORTICORD | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
| EP-0254670-A1 | 11-beta-(4-isopropenylphenyl)-estra-4,9-diene, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-01-27 | — | — | EP | disclosed |