SCHEMBL4664713

SCHEMBL4664713

CC(=O)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)/C=C\CO)[C@@H]3CCC4=CC(=O)CCC4=C32)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 7/20 0.67
▸ NR3C1 P04150 13/20 0.63
▸ PGR P06401 11/20 0.63
▸ ESR1 P03372 3/20 0.56
▸ NR3C2 P08235 2/20 0.56
▸ ESR2 Q92731 2/20 0.56
▸ THRA P10827 1/20 0.56
▸ OPRM1 P35372 2/20 0.54
▸ CYP3A4 P08684 3/20 0.53
▸ CYP2D6 P10635 3/20 0.53
▸ CYP2C19 P33261 3/20 0.53
▸ CYP2C9 P11712 3/20 0.53
▸ CYP1A2 P05177 2/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ LMNA P02545 2/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ TP53 P04637 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399827 1.00 AR (0.67) ARNR3C1PGRESR1NR3C2
SCHEMBL3678661 1.00 AR (0.67) ARNR3C1PGRESR1NR3C2
SCHEMBL15094157 1.00 AR (0.67) ARNR3C1PGRESR1NR3C2
SCHEMBL9146687 0.94 AR (0.58) ARNR3C1PGRESR1NR3C2
SCHEMBL14656547 0.92 AR (0.57) ARNR3C1PGRESR1NR3C2
SCHEMBL9740103 0.92 AR (0.57) ARNR3C1PGRESR1NR3C2
SCHEMBL14666086 0.92 AR (0.57) ARNR3C1PGRESR1NR3C2
SCHEMBL20235298 0.92 AR (0.57) ARNR3C1PGRESR1NR3C2
SCHEMBL5395107 0.92 AR (0.71) ARNR3C1PGRESR1NR3C2
SCHEMBL5395109 0.92 AR (0.71) ARNR3C1PGRESR1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1239829-B1 DEVICES FOR THE DELIVERY OF DRUGS HAVING ANTIPROGESTINIC PROPERTIES BAYER SCHERING PHARMA OY (FI) 2008-07-23 — — EP claimed
EP-0787002-B1 COMPETITIVE PROGESTERONE ANTAGONISTS FOR REGULATING FEMALE FERTILITY AS REQUIRED SCHERING AG (DE) 2006-12-13 — — EP claimed
EP-0889727-B1 SEQUENTIAL OESTROGEN/PROGESTERONE ANTAGONIST COMBINATION FOR HORMONE REPLACEMENT THERAPY SCHERING AG (DE) 2006-03-08 — — EP claimed
US-20050064031-A1 Combination contraceptive, kits that contain the latter, and a method that uses the latter BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-03-24 — — US claimed
US-6362237-B1 MIXTURE SCHERING AKTIENGESELLSCHAFT (DE) 2002-03-26 — — US claimed
US-6143754-A Competitive progesterone antagonist for demand-oriented female birth control SCHERING AKTIENGESELLSCHAFT (DE) 2000-11-07 — — US claimed
US-5089635-A Antiprogesterone, antiglucocorticoids SCHERING AKTIENGESELLSCHAFT (DE) 1992-02-18 — — US claimed
EP-2779996-B1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM KYMMENE CORP (FI) 2024-04-10 — — EP disclosed
US-11389537-B2 Drug delivery system for sustained delivery of bioactive agents UPM-KYMMENE CORPORATION (FI) 2022-07-19 — — US disclosed
US-20140322327-A1 DRUG DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF BIOACTIVE AGENTS UPM-KYMMENE CORPORATION (FI) 2014-10-30 — — US disclosed
EP-1239829-B1 DEVICES FOR THE DELIVERY OF DRUGS HAVING ANTIPROGESTINIC PROPERTIES BAYER SCHERING PHARMA OY (FI) 2008-07-23 — — EP disclosed
EP-0787002-B1 COMPETITIVE PROGESTERONE ANTAGONISTS FOR REGULATING FEMALE FERTILITY AS REQUIRED SCHERING AG (DE) 2006-12-13 — — EP disclosed
US-20020169205-A1 Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-11-14 — — US disclosed
US-6143754-A Competitive progesterone antagonist for demand-oriented female birth control SCHERING AKTIENGESELLSCHAFT (DE) 2000-11-07 — — US disclosed
EP-0723439-B1 COMBINATION OF PROGESTERONE ANTAGONISTS AND ANTI-OESTROGENS WITH PARTIAL AGONISTIC ACTION FOR USE IN HORMONE-REPLACEMENT THERAPY FOR PERI- AND POST-MENOPAUSAL WOMEN SCHERING AG (DE) 2000-09-13 — — EP disclosed
US-6040340-A NITRIC OXIDE SYNTHASE SUBSTRATE SCHERING AKTIENGESELLSCHAFT (DE) 2000-03-21 — — US disclosed
US-5719136-A Combination of progesterone antagonists and antiestrogens with partial agonistic action for hormone substitution therapy for perimenopausal and postmenopausal women SCHERING AKTIENGESELLSCHAFT (DE) 1998-02-17 — — US disclosed
US-5089635-A Antiprogesterone, antiglucocorticoids SCHERING AKTIENGESELLSCHAFT (DE) 1992-02-18 — — US disclosed
EP-0190759-B1 11-BETA PHENYL GONANES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1989-08-30 — — EP disclosed
EP-0190759-A2 11-Beta phenyl gonanes, their preparation and pharmaceutical compositions containing them SCHERING AKTIENGESELLSCHAFT (DE) 1986-08-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050064031-A1 Combination contraceptive, kits that contain the latter, and a method that uses the latter GNRHR, PGRMC2, SHBG AR 244/4885NR3C1 120/4885PGR 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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