⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147376 | 0.85 | — | — | |
| SCHEMBL9147130 | 0.81 | — | — | |
| SCHEMBL4921951 | 0.71 | — | — | |
| SCHEMBL4922216 | 0.71 | PTGIR (0.32) | — | |
| SCHEMBL4928277 | 0.68 | — | — | |
| SCHEMBL4929554 | 0.68 | — | — | |
| SCHEMBL2069121 | 0.67 | CPN1 (0.34) | — | |
| SCHEMBL12951778 | 0.66 | ADH1B (0.31) | — | |
| SCHEMBL15403780 | 0.66 | — | — | |
| SCHEMBL887216 | 0.66 | ADH1B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416231-A | Prostaglandin I2 derivatives | ASAHI GLASS COMPANY, LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0553352-B1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS CO LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0553352-A1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS COMPANY LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992004339-A1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS COMPANY LTD. (JP) | 1992-03-19 | — | — | WO | disclosed |