Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372270 | 0.92 | — | — | |
| SCHEMBL20447536 | 0.87 | — | — | |
| SCHEMBL14899026 | 0.82 | DPP4 (0.30) | — | |
| SCHEMBL873936 | 0.82 | DPP4 (0.30) | — | |
| SCHEMBL10475869 | 0.81 | — | — | |
| SCHEMBL25785485 | 0.81 | TDP1 (0.33) | TDP1 | |
| SCHEMBL25515507 | 0.81 | TDP1 (0.33) | TDP1 | |
| SCHEMBL26998009 | 0.81 | — | — | |
| SCHEMBL11641948 | 0.80 | TSHR (0.30) | — | |
| SCHEMBL11333467 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618284-B2 | Methods of preparing polymorphic form A of bazedoxifene acetate | WYETH LLC (US) | 2013-12-31 | — | — | US | disclosed |
| EP-2252585-B1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | WYETH LLC (US) | 2013-11-06 | — | — | EP | disclosed |
| US-20130018184-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | WYETH LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-8183367-B2 | Methods of preparing polymorphic form A of bazedoxifene acetate | WYETH LLC (US) | 2012-05-22 | — | — | US | disclosed |
| US-8063041-B2 | Polymorphic Form D of bazedoxifene acetate and methods of preparing same | WYETH LLC (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110021504-A1 | POLYMORPHIC FORM D OF BAZEDOXIFENE ACETATE AND METHODS OF PREPARING SAME | WYETH LLC | 2011-01-27 | — | — | US | disclosed |
| EP-2252585-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | Wyeth LLC (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100016581-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | WYETH (US) | 2010-01-21 | — | — | US | disclosed |
| WO-2009102773-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | WYETH (US) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016581-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | CYP19A1, CYP2A13, CYP26A1 | TDP1 2936/4885 |
| US-20110021504-A1 | POLYMORPHIC FORM D OF BAZEDOXIFENE ACETATE AND METHODS OF PREPARING SAME | CYP19A1, BRCA1, SHBG | TDP1 1748/4885 |
| US-20130018184-A1 | METHODS OF PREPARING POLYMORPHIC FORM A OF BAZEDOXIFENE ACETATE | CYP19A1, CYP2A13, CYP26A1 | TDP1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.