SCHEMBL9147108

SCHEMBL9147108

CC(C)(C)OOC(C)(CCC(=O)NNC(=O)c1ccccc1)OOC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
POLB P06746 2/20 0.46
CYP2C9 P11712 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
DUSP3 P51452 1/20 0.45
PTPN5 P54829 1/20 0.45
PTPN11 Q06124 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
CYP1A2 P05177 1/20 0.45
ATM Q13315 1/20 0.45
PRMT5 O14744 1/20 0.44
WDR77 Q9BQA1 1/20 0.44
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148161 0.82 ALDH1A1 (0.40) ALDH1A1L3MBTL1SMN1; SMN2TDP1MEN1
SCHEMBL12768690 0.77 KDM4E (0.61) ALDH1A1KDM4EL3MBTL1POLBCYP2C9
SCHEMBL563042 0.76 MEN1 (0.72) ALDH1A1KDM4EL3MBTL1POLBTDP1
SCHEMBL5673419 0.74 POLB (0.65) ALDH1A1KDM4EL3MBTL1POLBCYP2C9
SCHEMBL12323197 0.73 POLB (0.69) ALDH1A1KDM4EPOLBTDP1MEN1
SCHEMBL12768681 0.72 POLB (0.67) ALDH1A1KDM4EPOLBTDP1MEN1
SCHEMBL12768688 0.72 POLB (0.67) ALDH1A1KDM4EPOLBTDP1MEN1
SCHEMBL12768686 0.72 POLB (0.67) ALDH1A1KDM4EPOLBTDP1MEN1
SCHEMBL12768694 0.71 ALDH1A1 (0.68) ALDH1A1POLBSMN1; SMN2TDP1MEN1
SCHEMBL10591379 0.71 POLB (0.75) ALDH1A1KDM4EL3MBTL1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP claimed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US claimed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP claimed
US-5457162-A Catalyst for addition polymerization, curing and crosslinking ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-10-10 US disclosed
US-5399630-A Process for curing polymers using amino or hydrazino peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-03-21 US disclosed
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP disclosed
US-5360867-A Reactive with maleic acid or maleic anhydride polymer ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-11-01 US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP disclosed