Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038162 | 0.93 | TSHR (0.34) | TSHRALDH1A1HPGDCA1CA2 | |
| SCHEMBL9150427 | 0.93 | TSHR (0.34) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL9146271 | 0.91 | TSHR (0.38) | TSHRHPGDCA1CA2 | |
| SCHEMBL9147389 | 0.91 | TSHR (0.38) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL9145843 | 0.91 | TSHR (0.38) | TSHRHPGDCA1CA2 | |
| SCHEMBL1034224 | 0.88 | — | — | |
| SCHEMBL2418551 | 0.88 | — | — | |
| SCHEMBL9150049 | 0.87 | TSHR (0.38) | TSHRALDH1A1CA1CA2 | |
| SCHEMBL131510 | 0.85 | TSHR (0.39) | TSHRALDH1A1HPGDADRB2ADRB1 | |
| SCHEMBL9149280 | 0.85 | TSHR (0.41) | TSHRHPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668259-A1 | A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5434302-A | Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | PARADIES H HENRICH (DE) | 1995-07-18 | — | — | US | disclosed |