Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150427 | 0.98 | TSHR (0.34) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL9149090 | 0.94 | TSHR (0.41) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL1035588 | 0.94 | TSHR (0.41) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL9149280 | 0.94 | TSHR (0.41) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL19582089 | 0.94 | TSHR (0.41) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL9150049 | 0.92 | TSHR (0.38) | TSHRALDH1A1LPAR2LPAR3LPAR1 | |
| SCHEMBL9147185 | 0.91 | TSHR (0.33) | TSHRHPGDALDH1A1ADRB2ADRB1 | |
| SCHEMBL9146271 | 0.88 | TSHR (0.38) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL9145843 | 0.88 | TSHR (0.38) | TSHRHPGDLPAR2LPAR3LPAR1 | |
| SCHEMBL9149956 | 0.87 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668259-A1 | A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5434302-A | Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | PARADIES H HENRICH (DE) | 1995-07-18 | — | — | US | disclosed |