SCHEMBL9147189

SCHEMBL9147189

CCCCCSCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 12/20 0.53
PTGER3 P43115 7/20 0.53
PTGER2 P43116 6/20 0.53
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 2/20 0.43
ALDH1A1 P00352 1/20 0.40
ACE P12821 2/20 0.37
GMNN O75496 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
CYP2C9 P11712 1/20 0.37
BLM P54132 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9150781 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9151785 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9152671 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9148239 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9154781 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9148875 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9150836 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9151773 0.99 PTGER4 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9152845 0.96 PTGER4 (0.51) PTGER4PTGER3PTGER2MEN1KMT2A
SCHEMBL9152263 0.86 MEN1 (0.52) PTGER4PTGER3PTGER2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5472946-A Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes DISCOVERY THERAPEUTICS, INC. 1995-12-05 US disclosed
US-5470848-A Penetration enhancers for transdermal delivery of systemic agents DISCOVERY THERAPEUTICS, INC. 1995-11-28 US disclosed
US-5444075-A Penetration enhancers for transdermal delivery of systemic agents MINASKANIAN GEVORK (US) 1995-08-22 US disclosed
US-5234959-A Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream WHITBY RESEARCH, INC. (US) 1993-08-10 US disclosed
US-5118676-A Administering carboxylic derivatives as enhancer with systemically active agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
US-5118692-A Penetration enhances for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
US-4996199-A Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1991-02-26 US disclosed