SCHEMBL9152263

SCHEMBL9152263

CCCCCN1C(=O)CCC1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
PTGER4 P35408 12/20 0.49
PTGER3 P43115 9/20 0.49
PTGER2 P43116 8/20 0.49
ALDH1A1 P00352 2/20 0.47
ACE P12821 2/20 0.42
GBA1 P04062 1/20 0.41
USP2 O75604 1/20 0.41
P2RX7 Q99572 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10343416 1.00 MEN1 (0.52) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748862 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL242586 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748934 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761610 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL3425106 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8754825 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8749215 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8761736 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3
SCHEMBL8748944 0.98 MEN1 (0.51) MEN1KMT2APOLBPTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0187052-B1 ADAMANTAN AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM S.A. PANMEDICA Société dite: (FR) 1990-01-31 EP claimed
JP-6145141-A None JP disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
US-20230414481-A1 Composition and Method for Producing Same and Cosmetic Agent ASAHI KASEI FINECHEM CO., LTD. (JP) 2023-12-28 US disclosed
EP-4239037-A1 COMPOSITION, METHOD FOR PRODUCING SAME, AND COSMETIC Asahi Kasei Finechem Co., Ltd. (JP) 2023-09-06 EP disclosed
CN-116507696-A Composition, method for producing same, and cosmetic 旭化成精细化工股份有限公司 2023-07-28 CN disclosed
US-11377443-B2 Pharmaceutical compounds CellCentric Limited (GB) 2022-07-05 US disclosed
US-20200407349-A1 PHARMACEUTICAL COMPOUNDS CellCentric Limited (GB) 2020-12-31 US disclosed
US-10696666-B2 Pharmaceutical compounds CellCentric Limited (GB) 2020-06-30 US disclosed
US-10647704-B2 Pharmaceutical compounds CELLCENTRIC LTD (GB) 2020-05-12 US disclosed
CN-110049983-A Medical compounds 细胞中心有限公司 2019-07-23 CN disclosed
CN-110036002-A Medical compounds 细胞中心有限公司 2019-07-19 CN disclosed
US-5472946-A Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes DISCOVERY THERAPEUTICS, INC. 1995-12-05 US disclosed
US-5470848-A Penetration enhancers for transdermal delivery of systemic agents DISCOVERY THERAPEUTICS, INC. 1995-11-28 US disclosed
US-5444075-A Penetration enhancers for transdermal delivery of systemic agents MINASKANIAN GEVORK (US) 1995-08-22 US disclosed
JP-H06145141-A N-ACYL-2-PYRROLIDONE-5-CARBOXYLIC ACID ESTER AJINOMOTO CO INC 1994-05-24 JP disclosed
US-5234959-A Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream WHITBY RESEARCH, INC. (US) 1993-08-10 US disclosed
US-5118676-A Administering carboxylic derivatives as enhancer with systemically active agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
US-5118692-A Penetration enhances for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1992-06-02 US disclosed
US-4996199-A Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1991-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407349-A1 PHARMACEUTICAL COMPOUNDS EP300, HDAC1, HDAC11 MEN1 1691/4885KMT2A 458/4885POLB 2037/4885
US-20230414481-A1 Composition and Method for Producing Same and Cosmetic Agent CUTA, NOTUM, DAGLA MEN1 802/4885KMT2A 2484/4885POLB 218/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH MEN1 4840/4885KMT2A 2718/4885POLB 2615/4885
US-10647704-B2 Pharmaceutical compounds EP300, HDAC1, HDAC11 MEN1 1032/4885KMT2A 214/4885POLB 1379/4885
US-11377443-B2 Pharmaceutical compounds EP300, HDAC1, HDAC11 MEN1 1691/4885KMT2A 458/4885POLB 2037/4885
US-10696666-B2 Pharmaceutical compounds EP300, HDAC1, HDAC11 MEN1 1691/4885KMT2A 458/4885POLB 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.