Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147249 | 1.00 | LMNA (0.64) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9147269 | 1.00 | LMNA (0.64) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| Cetefloxacin SCHEMBL9147891 | 0.90 | EPHA2 (0.54) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| Cetefloxacin SCHEMBL9147898 | 0.90 | EPHA2 (0.54) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| Cetefloxacin SCHEMBL1230055 | 0.90 | EPHA2 (0.54) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9213760 | 0.89 | LMNA (0.50) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9046654 | 0.87 | LMNA (0.62) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10663315 | 0.86 | LMNA (0.68) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9146445 | 0.83 | PIM1 (0.49) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9146453 | 0.83 | PIM1 (0.49) | LMNAKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388298-B1 | Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines | ESTEVE LABOR DR (ES) | 1995-06-21 | — | — | EP | claimed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | disclosed |