⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674778 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL97667 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL28238644 | 0.75 | CYP3A4 (0.31) | — | |
| SCHEMBL9438529 | 0.74 | — | — | |
| SCHEMBL5681513 | 0.74 | — | — | |
| SCHEMBL846203 | 0.73 | — | — | |
| SCHEMBL846201 | 0.73 | — | — | |
| SCHEMBL1935132 | 0.73 | — | — | |
| SCHEMBL9611252 | 0.73 | — | — | |
| SCHEMBL1935136 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415208-B1 | Use of polysiloxane-polyoxyalkylene block copolymers in the preparation of rigid polyurethane foams | GOLDSCHMIDT AG TH (DE) | 1995-01-11 | — | — | EP | disclosed |
| EP-0415208-A2 | Use of polysiloxane-polyoxyalkylene block copolymers in the preparation of rigid polyurethane foams | Th. Goldschmidt AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0092700-B1 | PROCESS FOR PRODUCING HIGHLY RESILIENT COLD-CURING POLYURETHANE FOAMS | Th. Goldschmidt AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0092700-A1 | Process for producing highly resilient cold-curing polyurethane foams | Th. Goldschmidt AG (DE) | 1983-11-02 | — | — | EP | disclosed |