Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312423 | 1.00 | LMNA (0.57) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL9147402 | 1.00 | LMNA (0.57) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL11819609 | 0.83 | LMNA (0.61) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL11819614 | 0.83 | LMNA (0.61) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL946717 | 0.81 | LMNA (0.56) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL946716 | 0.81 | LMNA (0.56) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL945483 | 0.79 | LMNA (0.53) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL945484 | 0.79 | LMNA (0.53) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL9494278 | 0.78 | LMNA (0.52) | LMNARECQLMAPTMAPK1TSHR | |
| SCHEMBL9494274 | 0.78 | LMNA (0.52) | LMNARECQLMAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378719-A | Antiarthritic agents; rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0548018-A1 | Imidazoles | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |
| US-4582841-A | ANTITUMOR AND -CARCINOGENIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0085275-B1 | SUBSTITUTED THIAZOLIDINYLIC ESTERS OF MINERAL ACIDS | CIBA-GEIGY AG (CH) | 1986-02-19 | — | — | EP | disclosed |
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | disclosed |
| EP-0085275-A1 | Substituted thiazolidinylic esters of mineral acids | CIBA-GEIGY AG (CH) | 1983-08-10 | — | — | EP | disclosed |