Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539670 | 0.81 | ALDH1A1 (0.49) | CNR2NPC1MAPTMEN1KMT2A | |
| SCHEMBL9147770 | 0.80 | CNR2 (0.48) | HPGDCNR2UTS2RMDM2MEN1 | |
| SCHEMBL5745792 | 0.79 | ACACB (0.56) | CNR2ACACBMAPTMEN1KMT2A | |
| SCHEMBL11749960 | 0.78 | HPGD (0.62) | HPGDCNR2UTS2RMDM2PTGS2 | |
| SCHEMBL13182705 | 0.78 | HPGD (0.62) | HPGDCNR2UTS2RPTGS2NPC1 | |
| SCHEMBL11755702 | 0.78 | HPGD (0.62) | HPGDCNR2UTS2RMDM2PTGS2 | |
| SCHEMBL5444947 | 0.78 | HPGD (0.62) | HPGDCNR2UTS2RMDM2PTGS2 | |
| SCHEMBL13116493 | 0.78 | UTS2R (0.59) | HPGDCNR2UTS2RPTGS2TRPA1 | |
| SCHEMBL28987199 | 0.77 | MDM2 (0.58) | HPGDMDM2PTGS2NPC1MAPT | |
| SCHEMBL28987197 | 0.77 | MDM2 (0.58) | HPGDMDM2PTGS2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655057-A1 | CYANOGUANIDINES AS POTASSIUM CHANNEL BLOCKERS. | UPJOHN CO (US) | 1995-05-31 | — | — | EP | disclosed |
| US-5403852-A | Antiinflammatory agents | LABORATOIRE ROGER BELLON (FR) | 1995-04-04 | — | — | US | disclosed |