Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916276 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL916328 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL11416914 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL915278 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL915426 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL914643 | 0.96 | NPSR1 (0.46) | NPSR1KCNH2POLBACHEHPGD | |
| SCHEMBL914023 | 0.79 | L3MBTL1 (0.36) | POLBHPGDNR1I2MEN1KMT2A | |
| SCHEMBL916258 | 0.79 | POLB (0.41) | POLBACHEMEN1KMT2A | |
| SCHEMBL914642 | 0.79 | POLB (0.41) | POLBACHEMEN1KMT2A | |
| SCHEMBL563856 | 0.79 | NPSR1 (0.50) | NPSR1KCNH2POLBACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868126-B2 | Process for producing polyester, polyester produced using said process, and polyester molded product | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20080249280-A1 | Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2008-10-09 | — | — | US | disclosed |