SCHEMBL9147682

SCHEMBL9147682

CC(O)C(N)CCCCN

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.48
TRPA1 O75762 1/20 0.48
GSR P00390 1/20 0.43
SPHK1 Q9NYA1 2/20 0.41
NOS2 P35228 2/20 0.37
RNPEP Q9H4A4 1/20 0.37
NFKB1 P19838 1/20 0.35
CYP2D6 P10635 2/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20082267 1.00 TRPV1 (0.48) TRPV1TRPA1GSRSPHK1NOS2
SCHEMBL20537160 0.98 TRPV1 (0.52) TRPV1TRPA1GSRSPHK1NOS2
SCHEMBL16297104 0.92
SCHEMBL25975423 0.81
SCHEMBL8745700 0.81
SCHEMBL6157769 0.80 SPHK1 (0.58) TRPV1TRPA1SPHK1CYP2D6GMNN
SCHEMBL20388835 0.79 TRPV1 (0.48) TRPV1TRPA1GSRSPHK1CYP2D6
SCHEMBL24515068 0.79 GSR (0.46) TRPV1TRPA1GSRSPHK1RNPEP
SCHEMBL13532953 0.79 GSR (0.41) TRPV1TRPA1GSRNFKB1LMNA
Hydrochloric Acid SCHEMBL11197477 0.79 TRPV1 (0.40) TRPV1TRPA1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4918235-A POLYURETHANE CHAIN EXTENTERS BAYER AKTIENGESELLSCHAFT (DE) 1990-04-17 US claimed
EP-0325941-A2 Process for the preparation of modified polyisocyanates, polyisocyanates so obtained and their use BAYER AG (DE) 1989-08-02 EP claimed
EP-0302338-A1 1,5-Diaminoheptanol-6, a process for its preparation and its use BAYER AG (DE) 1989-02-08 EP claimed
JP-1066148-A None JP disclosed
JP-2003410-A None JP disclosed
CN-117430517-A Alcoholic carbonate salts derived from C4-C6 alkanediamines and blowing agent compositions 山东理工大学 2024-01-23 CN disclosed
EP-0418639-B1 Process for the preparation of uretdion-group containing polyisocyanates BASF AG (DE) 1995-01-04 EP disclosed
US-4918235-A POLYURETHANE CHAIN EXTENTERS BAYER AKTIENGESELLSCHAFT (DE) 1990-04-17 US disclosed
US-4918235-A POLYURETHANE CHAIN EXTENTERS BAYER AKTIENGESELLSCHAFT (DE) 1990-04-17 US disclosed
JP-H023410-A PRODUCTION OF POLYISOCYANATE CONTAINING BIURET GROUP AND URETDIONE GROUP BAYER AG 1990-01-09 JP disclosed
EP-0325941-A2 Process for the preparation of modified polyisocyanates, polyisocyanates so obtained and their use BAYER AG (DE) 1989-08-02 EP disclosed
EP-0302338-A1 1,5-Diaminoheptanol-6, a process for its preparation and its use BAYER AG (DE) 1989-02-08 EP disclosed
EP-0302338-A1 1,5-Diaminoheptanol-6, a process for its preparation and its use BAYER AG (DE) 1989-02-08 EP disclosed
EP-0302338-A1 1,5-Diaminoheptanol-6, a process for its preparation and its use BAYER AG (DE) 1989-02-08 EP disclosed