SCHEMBL9148162

SCHEMBL9148162

O=c1cc(-c2cccc(O)c2O)oc2cc(O)cc(O)c12

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.79
KMT2A Q03164 8/20 0.79
CYP3A4 P08684 6/20 0.79
MAPT P10636 6/20 0.79
TP53 P04637 5/20 0.79
CYP2D6 P10635 5/20 0.79
CYP2C9 P11712 5/20 0.79
CYP2C19 P33261 5/20 0.79
MAPK1 P28482 3/20 0.79
NEU2 Q9Y3R4 1/20 0.79
BACE1 P56817 3/20 0.69
TYR P14679 2/20 0.69
PTPN1 P18031 1/20 0.69
PTGS1 P23219 1/20 0.69
PTPN12 Q05209 1/20 0.69
PTPN22 Q9Y2R2 1/20 0.69
HPGD P15428 6/20 0.69
ALDH1A1 P00352 5/20 0.69
GABRP O00591 4/20 0.69
GABRD O14764 4/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3708991 0.88 MEN1 (1.00) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL1524141 0.87 BACE1 (0.76) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL30721041 0.85 CYP3A4 (0.69) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL8158889 0.84 MEN1 (0.71) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL29924112 0.84 MEN1 (0.71) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL3703230 0.82 MEN1 (0.69) MEN1KMT2ACYP3A4MAPTTP53
Norartocarpetin SCHEMBL29435851 0.82 BACE1 (1.00) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL29424233 0.82 BACE1 (0.77) MEN1KMT2ACYP3A4MAPTTP53
SCHEMBL14464104 0.82 BACE1 (0.77) MEN1KMT2ACYP3A4MAPTTP53
Norartocarpetin SCHEMBL1546435 0.82 BACE1 (1.00) MEN1KMT2ACYP3A4MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5414015-A Administering a polyhydroxyflavone TSUJIMOTO KAGAKU KOGYO CO., LTD. (JP) 1995-05-09 US claimed
JP-5025041-A None JP disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
CN-110812887-A Transmembrane protein liposome silica gel compound and preparation method and application thereof 中国人民解放军第二军医大学 2020-02-21 CN disclosed
WO-2012096494-A9 AGENT CONTAINING B-RING-SUBSTITUTED FLAVONOID DERIVATIVES FOR TREATING ARTHRITIS 강원대학교 산학협력단 (KR) 2013-01-24 WO disclosed
WO-2012096494-A2 AGENT CONTAINING B-RING-SUBSTITUTED FLAVONOID DERIVATIVES FOR TREATING ARTHRITIS 강원대학교 산학협력단 (KR) 2012-07-19 WO disclosed
US-5414015-A Administering a polyhydroxyflavone TSUJIMOTO KAGAKU KOGYO CO., LTD. (JP) 1995-05-09 US disclosed
JP-H0525041-A ANTI-CARCINOGENIC PROMOTER AGENT TSUJIMOTO KAGAKU KOGYO KK 1993-02-02 JP disclosed