SCHEMBL3708991

SCHEMBL3708991

O=c1cc(-c2ccccc2O)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 1.00
KMT2A Q03164 8/20 1.00
TP53 P04637 6/20 1.00
CYP3A4 P08684 6/20 1.00
MAPT P10636 6/20 1.00
CYP2D6 P10635 5/20 1.00
CYP2C9 P11712 5/20 1.00
CYP2C19 P33261 5/20 1.00
MAPK1 P28482 3/20 1.00
NEU2 Q9Y3R4 1/20 1.00
BACE1 P56817 3/20 0.78
TYR P14679 2/20 0.78
PTPN1 P18031 1/20 0.78
PTGS1 P23219 1/20 0.78
PTPN12 Q05209 1/20 0.78
PTPN22 Q9Y2R2 1/20 0.78
HPGD P15428 6/20 0.77
ALDH1A1 P00352 5/20 0.77
GABRP O00591 4/20 0.77
GABRD O14764 4/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148162 0.88 MEN1 (0.79) MEN1KMT2ATP53CYP3A4MAPT
Norartocarpetin SCHEMBL29435851 0.88 BACE1 (1.00) MEN1KMT2ATP53CYP3A4MAPT
Norartocarpetin SCHEMBL1546435 0.88 BACE1 (1.00) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL13259767 0.87 MEN1 (1.00) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL8477643 0.87 GABRP (1.00) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL4649638 0.86 MEN1 (0.78) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL28349263 0.85 BACE1 (0.83) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL29435855 0.85 CYP3A4 (0.76) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL26117399 0.85 CYP3A4 (0.76) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL14464104 0.84 BACE1 (0.77) MEN1KMT2ATP53CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE MEDIENCE CO., LTD. (KR) 2023-04-20 US claimed
EP-0859557-B1 FOODS AND BEVERAGES CONTAINING ANTHOCYANINS STABILIZED BY PLANT EXTRACTS NATUREX INC (US) 2007-03-21 EP claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
EP-1435930-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-07-14 EP claimed
WO-2003032969-A2 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-04-24 WO claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
US-5414015-A Administering a polyhydroxyflavone TSUJIMOTO KAGAKU KOGYO CO., LTD. (JP) 1995-05-09 US claimed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP claimed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO claimed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP claimed
JP-5025041-A None JP disclosed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
US-20250263774-A1 DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD UNIV NORTH TEXAS (US) 2025-08-21 US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP disclosed
JP-H0525041-A ANTI-CARCINOGENIC PROMOTER AGENT TSUJIMOTO KAGAKU KOGYO KK 1993-02-02 JP disclosed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP disclosed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO disclosed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119060-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING, AS ACTIVE INGREDIENT, COMPLEX OF BIGUANIDE-BASED COMPOUND AND FLAVONE, HYDROXYFLAVONE, FLAVANONE, FLAVONE DERIVATIVE, HYDROXYFLAVONE DERIVATIVE, OR FLAVANONE DERIVATIVE SLC5A2, SLC5A1, SLC5A6 MEN1 617/4885KMT2A 1807/4885TP53 134/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL MEN1 3411/4885KMT2A 1142/4885TP53 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.