SCHEMBL9148451

SCHEMBL9148451

CN(C)c1ccc(-c2nnc(-c3ccccn3)c(-c3ccccn3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
HIF1A Q16665 4/20 0.57
LMNA P02545 3/20 0.57
MITF O75030 1/20 0.57
DCTPP1 Q9H773 1/20 0.45
CYP1A2 P05177 3/20 0.44
HTT P42858 1/20 0.44
TP53 P04637 2/20 0.43
NPC1 O15118 2/20 0.43
SYK P43405 1/20 0.43
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
CYP2C19 P33261 2/20 0.41
GLA P06280 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5590717 0.83 HIF1A (0.59) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL5590434 0.79 SMN1; SMN2 (0.62) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL5590610 0.79 SMN1; SMN2 (0.62) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL5590833 0.78 TP53 (0.65) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL31054349 0.78 DCTPP1 (0.52) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL210344 0.78 DCTPP1 (0.52) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL31400293 0.75 KDM4E (0.50) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL21988543 0.75 KDM4E (0.50) KDM4ESMN1; SMN2HIF1ALMNAMITF
SCHEMBL12907125 0.73 KDM4E (0.51) KDM4ESMN1; SMN2HIF1ALMNADCTPP1
SCHEMBL5590017 0.72 HIF1A (0.66) KDM4ESMN1; SMN2HIF1ALMNAMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5398105-A Method of electrophotographic wet reversal development MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-14 US disclosed
US-4520088-A COPOLYMER OF A STYRENE, AN ALKYL ACRYLATE WITH A C-4 OR GREATER ALKYL, AND A C-3 OR SMALLER ALKYL ACRYLATE MITSUBISHI PAPER MILLS, LTD. (JP) 1985-05-28 US disclosed
US-4499167-A Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-12 US disclosed
US-4477547-A POLYAMIDE BINDER MITSUBISHI PAPER MILLS, LTD. (JP) 1984-10-16 US disclosed
US-4461818-A ETHCING WITH SOLUTION OF ALKALI AND/OR ALCOHOL MITSUBISHI PAPER MILLS LTD. (JP) 1984-07-24 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed