Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 12/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.44 |
| ▸ | USP2 | O75604 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296067 | 0.87 | MEN1 (0.53) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL10623389 | 0.85 | NR4A1 (0.47) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL6825327 | 0.84 | MAPT (0.46) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL6824878 | 0.80 | MEN1 (0.67) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL138484 | 0.79 | MAP3K5 (0.65) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL12311502 | 0.75 | NR4A1 (0.79) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL13382720 | 0.75 | MEN1 (0.66) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL14559159 | 0.74 | MAP3K5 (0.61) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL17808609 | 0.73 | NR4A1 (0.52) | NR4A1MAPTSMN1; SMN2PABPC1MEN1 | |
| SCHEMBL14621981 | 0.73 | PABPC1 (0.42) | MAPTPABPC1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384377-A | Anthraquinone and anthrapyridone compounds provide neutral to blue hue to yellow-appearing polyesters | EASTMAN CHEMICAL COMPANY (US) | 1995-01-24 | — | — | US | disclosed |