SCHEMBL9149010

SCHEMBL9149010

Nc1ccc(N(N)N)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.55
TDP1 Q9NUW8 9/20 0.55
ALDH1A1 P00352 8/20 0.55
MAPK1 P28482 5/20 0.55
ALOX15 P16050 3/20 0.55
TP53 P04637 2/20 0.55
MAPT P10636 4/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TSHR P16473 5/20 0.48
GFER P55789 2/20 0.48
PSMD14 O00487 1/20 0.48
RECQL P46063 1/20 0.48
APP P05067 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369175 0.91 ALDH1A1 (0.61) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL2259243 0.81 TDP1 (0.70) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL18410886 0.80 CYP3A4 (0.55) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL308803 0.76 TDP1 (0.78) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL4519085 0.76 CYP3A4 (0.39) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL2009254 0.76 TDP1 (0.78) CYP3A4TDP1ALDH1A1MAPK1ALOX15
Hydrochloric Acid SCHEMBL31558767 0.73 CYP3A4 (0.74) CYP3A4TDP1ALDH1A1MAPK1ALOX15
Hydrochloric Acid SCHEMBL9238428 0.73 CYP3A4 (0.74) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL30901051 0.73 TDP1 (0.74) CYP3A4TDP1ALDH1A1MAPK1ALOX15
SCHEMBL320609 0.73 MEN1 (1.00) CYP3A4TDP1ALDH1A1MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111171324-B Load metal type environment-friendly ring crosslinked porous polyphosphazene and preparation method and application thereof 北京东方雨虹防水技术股份有限公司 2022-03-18 CN claimed
CN-111349244-B Preparation method of environment-friendly type cross-linked polyphosphazene 北京理工大学 2021-03-19 CN claimed
CN-111349244-A Preparation method of environment-friendly type cross-linked polyphosphazene 北京理工大学 2020-06-30 CN claimed
CN-111171324-A Load metal type environment-friendly ring crosslinked porous polyphosphazene and preparation method and application thereof 北京东方雨虹防水技术股份有限公司 2020-05-19 CN claimed
CN-111171324-B Load metal type environment-friendly ring crosslinked porous polyphosphazene and preparation method and application thereof 北京东方雨虹防水技术股份有限公司 2022-03-18 CN disclosed
CN-111349244-B Preparation method of environment-friendly type cross-linked polyphosphazene 北京理工大学 2021-03-19 CN disclosed
CN-111349244-A Preparation method of environment-friendly type cross-linked polyphosphazene 北京理工大学 2020-06-30 CN disclosed
CN-111171324-A Load metal type environment-friendly ring crosslinked porous polyphosphazene and preparation method and application thereof 北京东方雨虹防水技术股份有限公司 2020-05-19 CN disclosed
US-5420187-A Dispersant and monomer with polymerization catalyst and pigment TOYO INK MANUFACTURING CO., LTD. (JP) 1995-05-30 US disclosed
US-4866469-A Photosensitive material package unit provided with exposure function FUJI PHOTO FILM CO., LTD. (JP) 1989-09-12 US disclosed