Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144443 | 0.95 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL9141854 | 0.92 | AGTR1 (0.70) | AGTR1 | |
| SCHEMBL9566053 | 0.91 | AGTR1 (0.81) | AGTR1 | |
| L-159913 SCHEMBL9144158 | 0.91 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL9565941 | 0.91 | AGTR1 (0.86) | AGTR1 | |
| SCHEMBL9565949 | 0.91 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL9377635 | 0.90 | AGTR1 (0.87) | AGTR1 | |
| SCHEMBL9146679 | 0.90 | AGTR1 (0.80) | AGTR1 | |
| SCHEMBL29486807 | 0.90 | AGTR1 (0.87) | AGTR1 | |
| SCHEMBL9372471 | 0.90 | AGTR1 (0.80) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411980-A | Substituted triazolinones, triazolinethiones, and triazolinimines as angiotensin II antagonists | MERCK & CO., INC. (US) | 1995-05-02 | — | — | US | disclosed |
| US-5250558-A | Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis | MERCK & CO., INC. (US) | 1993-10-05 | — | — | US | disclosed |