Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149036 | 1.00 | MAPT (0.44) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL23515405 | 0.89 | MAPT (0.42) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL7796110 | 0.87 | MAPT (0.38) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL10890329 | 0.87 | MAPT (0.38) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9561752 | 0.87 | MAPT (0.38) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9306236 | 0.86 | KDM4E (0.43) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9720468 | 0.85 | KDM4E (0.36) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9720446 | 0.85 | KDM4E (0.36) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL9720443 | 0.85 | KDM4E (0.36) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL10924490 | 0.85 | MEN1 (0.38) | MAPTMEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |