Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149036 | 0.86 | MAPT (0.44) | KDM4ENPC1RAB9AGAADHODH | |
| SCHEMBL9149040 | 0.86 | MAPT (0.44) | KDM4ENPC1RAB9AGAADHODH | |
| SCHEMBL10375594 | 0.85 | USP2 (0.46) | KDM4ENPC1RAB9AGAADHODH | |
| SCHEMBL10863678 | 0.84 | MEN1 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL9561752 | 0.84 | MAPT (0.38) | KDM4ESMN1; SMN2GAADHODHMAPT | |
| SCHEMBL7796110 | 0.84 | MAPT (0.38) | KDM4ESMN1; SMN2GAADHODHMAPT | |
| SCHEMBL10890329 | 0.84 | MAPT (0.38) | KDM4ESMN1; SMN2GAADHODHMAPT | |
| SCHEMBL23515405 | 0.84 | MAPT (0.42) | KDM4EGAADHODHMAPTTDP1 | |
| SCHEMBL10628854 | 0.84 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2GAADHODHMAPT | |
| SCHEMBL10628848 | 0.84 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2GAADHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6073013-A | — | — | None | — | — | JP | disclosed |
| JP-H0673013-A | PRODUCTION OF QUINOLONECARBOXYLIC ACID DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1994-03-15 | — | — | JP | disclosed |