SCHEMBL9149162

SCHEMBL9149162

CCCCCCC(=O)Oc1ccc(-c2ccc(OCCC[C@@H](C)CC)c(Cl)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.45
PPARA Q07869 2/20 0.45
MAPT P10636 2/20 0.44
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTPN11 Q06124 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TRPV3 Q8NET8 1/20 0.40
S1PR1 P21453 1/20 0.39
ATM Q13315 1/20 0.39
TOP2A P11388 1/20 0.39
MAPK1 P28482 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN6 P29350 1/20 0.39
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9145224 1.00 PPARG (0.45) PPARGPPARAMAPTTHRATHRB
SCHEMBL9145944 1.00 PPARG (0.45) PPARGPPARAMAPTTHRATHRB
SCHEMBL9146036 0.91 ALOX15 (0.44) PPARGPPARAMAPTTHRATHRB
SCHEMBL9150204 0.91 ALOX15 (0.44) PPARGPPARAMAPTTHRATHRB
SCHEMBL9148886 0.91 ALOX15 (0.44) PPARGPPARAMAPTTHRATHRB
SCHEMBL9147238 0.88 PPARG (0.45) PPARGPPARATHRATHRBALOX15
SCHEMBL9145326 0.88 PPARG (0.45) PPARGPPARATHRATHRBALOX15
SCHEMBL9518615 0.88 PPARG (0.45) PPARGPPARATHRATHRBALOX15
SCHEMBL9147070 0.85 RARB (0.43) MAPTTHRATHRBALDH1A1TDP1
SCHEMBL9149724 0.85 RARB (0.43) MAPTTHRATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397504-A Liquid crystal KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-03-14 US disclosed
EP-0315701-B1 BIPHENYL COMPOUND KANTO KAGAKU (JP) 1993-12-29 EP disclosed
EP-0315701-A1 BIPHENYL COMPOUND KANTO KAGAKU KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed