Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | GRK2 | P25098 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242760 | 0.90 | ALDH1A1 (0.52) | KMT2AALDH1A1POLBAPAF1GRK2 | |
| SCHEMBL10891943 | 0.87 | KMT2A (0.58) | KMT2AALDH1A1POLBAPAF1GRK2 | |
| SCHEMBL9496059 | 0.82 | KMT2A (0.56) | KMT2AALDH1A1POLBAPAF1GRK2 | |
| SCHEMBL28417802 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1LMNAMEN1CASP6 | |
| SCHEMBL13294871 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1LMNAMEN1RXFP1 | |
| SCHEMBL11332784 | 0.81 | KMT2A (0.47) | KMT2AALDH1A1POLBAPAF1GRK2 | |
| SCHEMBL12916670 | 0.80 | KMT2A (0.60) | KMT2AALDH1A1LMNAMEN1RXFP1 | |
| SCHEMBL11142183 | 0.80 | CA1 (0.61) | KMT2AALDH1A1LMNAMEN1RXFP1 | |
| SCHEMBL30629806 | 0.80 | CA1 (0.61) | KMT2AALDH1A1LMNAMEN1RXFP1 | |
| SCHEMBL1553581 | 0.80 | KMT2A (0.63) | KMT2AALDH1A1POLBAPAF1GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | claimed |
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |
| US-4778911-A | INTERMEDIATES FOR FIBER-REACTIVE DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| US-4482501-A | REACTING AN AMINOARYL- OR AMIDOARYL-B- HYDROXYLETHYLSULFONE WITH SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |
| US-4346046-A | FROM AMINOARYL-B-HYDROXYETHYLSULFONE AND SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-24 | — | — | US | disclosed |