Methacrylic Acid

Methacrylic Acid

SCHEMBL9149254

C=C(C)C(=O)O.CCCC(=CC=C(CC)C(=O)O)C(=O)O

nearest known ligand 0.34

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
ALDH1A1 P00352 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3148391 0.90 FFAR3 (0.42) FFAR3HDAC3HDAC1HDAC2HDAC8
Methacrylic Acid SCHEMBL8082068 0.81
SCHEMBL28271264 0.79 HDAC3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL158310 0.78 FFAR3 (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL1537455 0.78 CES1 (0.42) ALDH1A1CES2CES1
SCHEMBL1003653 0.75 HDAC3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL3979241 0.75 CES1 (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL17061403 0.75 HDAC3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL1003654 0.75 HDAC3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
Methacrylic Acid SCHEMBL8898659 0.74 HDAC3 (0.43) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5405731-A Hydrophobic binder and addition polymer in protective layer with photoimageable coating containing carboxylic and unsaturated comonomers, photoinitiator and thermal crosslinking agent, for resistance to molten solder E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-11 US disclosed
US-5288589-A Storage stability E.I. DU PONT DE NEMOURS AND COMPANY 1994-02-22 US disclosed