Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17061403 | 1.00 | HDAC3 (0.40) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL1003654 | 1.00 | HDAC3 (0.40) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL8586760 | 0.87 | CES1 (0.41) | CES2CES1TSHRALDH1A1AKR1B1 | |
| SCHEMBL8586757 | 0.87 | CES1 (0.41) | CES2CES1TSHRALDH1A1AKR1B1 | |
| SCHEMBL28694016 | 0.85 | AKR1B1 (0.46) | CES2CES1TSHRALDH1A1AKR1B1 | |
| SCHEMBL31622773 | 0.84 | GPR84 (0.48) | CES2CES1TSHRALDH1A1AKR1B1 | |
| SCHEMBL19187723 | 0.83 | TSHR (0.32) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| SCHEMBL4584135 | 0.81 | — | — | |
| SCHEMBL17265275 | 0.81 | — | — | |
| SCHEMBL6669152 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115812710-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-112118739-B | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-11371063-B2 | Microorganisms and methods for the production of butadiene using acetyl-coA | GENOMATICA, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| CN-112118739-A | Insect repellent composition comprising one or more insect repellent fatty acids having 9 to 21 carbon atoms | 长荣置地有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-20200354753-A1 | MICROORGANISMS AND METHODS FOR THE PRODUCTION OF BUTADIENE USING ACETYL-COA | AGAIN BIO APS (DK) | 2020-11-12 | — | — | US | disclosed |
| US-9463173-B2 | Compositions and methods for treating obesity and obesity-related conditions | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20150250747-A1 | COMPOSITIONS AND METHODS FOR TREATING OBESITY AND OBESITY-RELATED CONDITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-09-10 | — | — | US | disclosed |
| EP-2694480-B1 | ADAMANTYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2015-03-04 | — | — | EP | disclosed |
| EP-2456433-A2 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | Biolink Life Sciences, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011376-A2 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | BIOLINK LIFE SCIENCES, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110015267-A1 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | BIOLINK LIFE SCIENCES, LLC | 2011-01-20 | — | — | US | disclosed |
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2006-10-05 | — | — | US | disclosed |
| WO-2004054957-A2 | VALPROIC ACID ANALOGUES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2004-07-01 | — | — | WO | disclosed |
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | MALT1, HDAC11, GABRA6 | HDAC3 8/4885HDAC1 5/4885HDAC2 14/4885 |
| US-20110015267-A1 | METHODS FOR THE PREPARATION AND USE OF AQUEOUS SOLUTIONS OF MAGNESIUM VALPROATE HYDRATE AND L-CARNITINE | SLC25A20, CPT1A, CPT1B | HDAC3 50/4885HDAC1 114/4885HDAC2 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.