Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 5/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146241 | 1.00 | PTPN11 (0.48) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL9145185 | 1.00 | PTPN11 (0.48) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL10526219 | 0.94 | MAPT (0.47) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL9148876 | 0.91 | MAPT (0.47) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL10526577 | 0.88 | NPC1 (0.49) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL10526226 | 0.88 | NPC1 (0.49) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL10526347 | 0.88 | NPC1 (0.49) | PTPN11THRATHRBNPC1MAPT | |
| SCHEMBL10455791 | 0.88 | THRA (0.55) | PTPN11THRATHRB | |
| SCHEMBL9150013 | 0.86 | PTPN11 (0.56) | PTPN11THRATHRBRAB9AALDH1A1 | |
| SCHEMBL9152800 | 0.86 | PTPN11 (0.45) | PTPN11THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |