Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501266 | 0.88 | PLAU (0.47) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL13989415 | 0.86 | CTDSP1 (0.41) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL11696503 | 0.85 | CTDSP1 (0.44) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL11696205 | 0.85 | CTDSP1 (0.44) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL11692926 | 0.83 | CTDSP1 (0.43) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL7628352 | 0.83 | CTDSP1 (0.43) | CTDSP1CA2HTR6APEX1NT5E | |
| SCHEMBL10626413 | 0.81 | NT5E (0.47) | CTDSP1CA2NT5EALDH1A1HSD17B10 | |
| SCHEMBL9097803 | 0.80 | CA1 (0.53) | CA2HTR6APEX1CA1CA9 | |
| SCHEMBL11426051 | 0.80 | APEX1 (0.49) | CA2HTR6APEX1TDP1 | |
| SCHEMBL11692932 | 0.80 | CTDSP1 (0.40) | CTDSP1CA2HTR6APEX1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0384265-B1 | PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0292904-B1 | WATER SOLUBLE NAPHTYL-AZO-PYRAZOLON COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4963661-A | MONOAZO DYES; FAST YELLOW TO ORANGE HUES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-16 | — | — | US | disclosed |
| EP-0384265-A1 | Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4948917-A | REACTING PHOSGENE AND BETA-HYDROXYETHYLSULFONYL-ARYLAMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0292904-A2 | Water soluble naphtyl-azo-pyrazolon compounds, process for their preparation and their use as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| US-4745187-A | Process for the preparation of water-soluble phthalocyanine dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |
| US-4485041-A | Water-soluble metal free or copper triazino-bis-[hydroxy-naphthylamino]-disazo dyestuffs containing fiber reactive groups, and a process for dyeing or printing cellulose fibers | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-27 | — | — | US | disclosed |
| US-4482501-A | REACTING AN AMINOARYL- OR AMIDOARYL-B- HYDROXYLETHYLSULFONE WITH SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |
| US-4346046-A | FROM AMINOARYL-B-HYDROXYETHYLSULFONE AND SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-24 | — | — | US | disclosed |
| US-4323497-A | Water-soluble disazo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |
| US-4045428-A | Water-soluble reactive naphthylazonaphthyl dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |