Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | ATIC | P31939 | 2/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149809 | 0.88 | CTDSP1 (0.47) | PLAUCA2HTR6APEX1CA1 | |
| SCHEMBL6562190 | 0.84 | PLAU (0.49) | PLAUCA2HTR6NSD2DUSP3 | |
| SCHEMBL7624190 | 0.83 | PLAU (0.43) | PLAUCA2HTR6APEX1NSD2 | |
| SCHEMBL29516390 | 0.80 | PLAU (0.56) | PLAUCA2HTR6APEX1NSD2 | |
| SCHEMBL342865 | 0.80 | PLAU (0.56) | PLAUCA2HTR6APEX1NSD2 | |
| SCHEMBL9097803 | 0.80 | CA1 (0.53) | CA2HTR6APEX1CA1CA9 | |
| SCHEMBL3849624 | 0.79 | PLAU (0.55) | PLAUCA2HTR6APEX1NSD2 | |
| SCHEMBL1346003 | 0.77 | CA2 (0.63) | PLAUCA2HTR6NSD2DUSP3 | |
| SCHEMBL30440356 | 0.77 | CA2 (0.63) | PLAUCA2HTR6NSD2DUSP3 | |
| SCHEMBL11426051 | 0.77 | APEX1 (0.49) | CA2HTR6APEX1NSD2ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384265-B1 | PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0384265-A1 | Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4948917-A | REACTING PHOSGENE AND BETA-HYDROXYETHYLSULFONYL-ARYLAMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| US-3957751-A | WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |