Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94759 | 0.86 | TSHR (0.48) | TSHRHTTPGDCYP2C9PDE4A | |
| SCHEMBL9547017 | 0.86 | TSHR (0.39) | TSHR | |
| SCHEMBL27625179 | 0.84 | TSHR (0.46) | TSHRHTTPGDCYP2C9PDE4A | |
| SCHEMBL27605067 | 0.84 | TSHR (0.46) | TSHRHTTMGAMGAASI | |
| SCHEMBL7035397 | 0.84 | TSHR (0.46) | TSHRHTTPGDCYP2C9PDE4A | |
| SCHEMBL28775765 | 0.82 | TSHR (0.36) | TSHR | |
| SCHEMBL1864896 | 0.82 | TSHR (0.43) | TSHRHTTPGDCYP2C9 | |
| SCHEMBL29232003 | 0.82 | TSHR (0.62) | TSHRHTTPGDCYP2C9PDE4A | |
| SCHEMBL9862728 | 0.82 | TSHR (0.62) | TSHRHTTPGDCYP2C9PDE4A | |
| SCHEMBL1397720 | 0.82 | TSHR (0.62) | TSHRHTTPGDCYP2C9PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443971-A | Pyranones | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |