Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151308 | 1.00 | ALDH1A1 (0.38) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9150714 | 1.00 | ALDH1A1 (0.38) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9785326 | 0.99 | ALDH1A1 (0.35) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9785318 | 0.99 | ALDH1A1 (0.35) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL8997261 | 0.99 | ALDH1A1 (0.35) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL10432609 | 0.95 | GAA (0.34) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9556158 | 0.95 | GAA (0.34) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9556141 | 0.95 | GAA (0.34) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9556155 | 0.95 | GAA (0.34) | ALDH1A1GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL9556286 | 0.95 | GAA (0.34) | ALDH1A1GRM2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395220-B1 | 1,3-dioxane derivative | SEIKO EPSON CORP (JP) | 1995-01-18 | — | — | EP | claimed |
| EP-0395220-A2 | 1,3-dioxane derivative | SEIKO EPSON CORPORATION (JP) | 1990-10-31 | — | — | EP | claimed |
| EP-0395220-B1 | 1,3-dioxane derivative | SEIKO EPSON CORP (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0395220-A2 | 1,3-dioxane derivative | SEIKO EPSON CORPORATION (JP) | 1990-10-31 | — | — | EP | disclosed |