Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18605874 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL25407758 | 0.80 | TAAR1 (0.58) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL828471 | 0.80 | TAAR1 (0.58) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3660921 | 0.78 | SLC6A2 (0.56) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL27782433 | 0.78 | SLC6A2 (0.55) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL4874067 | 0.77 | TAAR1 (0.54) | TAAR1ALDH1A1CYP3A4IDO1MAOB | |
| SCHEMBL10462120 | 0.77 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL872871 | 0.77 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL516033 | 0.77 | TAAR1 (0.73) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 | |
| Phentermine SCHEMBL26615 | 0.77 | SLC6A2 (1.00) | SLC6A2TAAR1CYP2D6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668259-A1 | A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5434302-A | Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | PARADIES H HENRICH (DE) | 1995-07-18 | — | — | US | disclosed |