SCHEMBL9150144

SCHEMBL9150144

CCCCCOc1ccc(-c2ccc(OCCC[C@@H](C)CC)c(F)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.46
RARA P10276 1/20 0.46
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
FAAH O00519 2/20 0.40
S1PR1 P21453 2/20 0.40
PTPN11 Q06124 2/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
NR5A1 Q13285 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
LTA4H P09960 2/20 0.38
PTPN1 P18031 1/20 0.37
PTPN6 P29350 1/20 0.37
S1PR4 O95977 1/20 0.37
S1PR3 Q99500 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148568 0.99 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9149720 0.99 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9150048 0.99 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9148458 0.99 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9221987 0.99 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9752264 0.96 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9150071 0.96 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9149632 0.96 RARB (0.45) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9149318 0.93 RARB (0.46) RARBRARACYP3A4CYP2D6FAAH
SCHEMBL9148124 0.92 THRA (0.44) S1PR1PTPN11THRATHRBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397504-A Liquid crystal KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-03-14 US disclosed
EP-0315701-B1 BIPHENYL COMPOUND KANTO KAGAKU (JP) 1993-12-29 EP disclosed
EP-0315701-A1 BIPHENYL COMPOUND KANTO KAGAKU KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed