Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | GRM8 | O00222 | 2/20 | 0.60 |
| ▸ | GRM6 | O15303 | 2/20 | 0.60 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.60 |
| ▸ | GSR | P00390 | 2/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL5574782 | 0.90 | CYP1A2 (0.64) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Glutamic Acid SCHEMBL3072013 | 0.85 | GRM8 (0.62) | CYP1A2GRM8GRM6GRM7GRM4 | |
| SCHEMBL374739 | 0.84 | SLC1A1 (0.54) | CYP1A2GRM8GRM6GRM7GRM4 | |
| SCHEMBL20473256 | 0.84 | SLC1A1 (0.54) | CYP1A2GRM8GRM6GRM7GRM4 | |
| SCHEMBL3425165 | 0.84 | SLC1A1 (0.54) | CYP1A2GRM8GRM6GRM7GRM4 | |
| D-Glutamate SCHEMBL28340743 | 0.83 | GRM8 (0.64) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Aspartic Acid SCHEMBL20394531 | 0.83 | GRIK1 (0.43) | CYP1A2SLC1A1GRIK1GRIA1GRIA2 | |
| Hydrochloric Acid SCHEMBL11267845 | 0.82 | SLC1A1 (0.52) | CYP1A2GRM8GRM6GRM7GRM4 | |
| Glutamic Acid SCHEMBL7659688 | 0.82 | GRM8 (0.82) | CYP1A2GRM8GRM6GRM7GRM4 | |
| D-Glutamate SCHEMBL28179651 | 0.81 | GRIK1 (0.53) | CYP1A2GRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614487-A4 | DNA ENCODING A GLYCINE TRANSPORTER AND USES THEREOF. | SYNAPTIC PHARMA CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0614487-A1 | DNA ENCODING A GLYCINE TRANSPORTER AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1994-09-14 | — | — | EP | disclosed |
| WO-1993010228-A1 | DNA ENCODING A GLYCINE TRANSPORTER AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1993-05-27 | — | — | WO | disclosed |