⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154662 | 0.95 | — | — | |
| SCHEMBL9153021 | 0.88 | — | — | |
| SCHEMBL9152808 | 0.88 | — | — | |
| SCHEMBL9154907 | 0.86 | — | — | |
| SCHEMBL9154893 | 0.86 | AGTR2 (0.41) | — | |
| SCHEMBL9249703 | 0.84 | — | — | |
| SCHEMBL9530791 | 0.84 | — | — | |
| SCHEMBL9154925 | 0.83 | — | — | |
| SCHEMBL9153671 | 0.83 | — | — | |
| SCHEMBL9527287 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389659-A | Hypotensive agents | GLAXO GROUP LIMITED (GB) | 1995-02-14 | — | — | US | claimed |
| WO-1993005025-A1 | C-LINKED PYRAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-03-18 | — | — | WO | claimed |
| EP-0446062-A1 | C-Linked pyrazole derivatives | GLAXO GROUP LIMITED (GB) | 1991-09-11 | — | — | EP | claimed |
| US-5389659-A | Hypotensive agents | GLAXO GROUP LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| WO-1993005025-A1 | C-LINKED PYRAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-03-18 | — | — | WO | disclosed |
| EP-0446062-A1 | C-Linked pyrazole derivatives | GLAXO GROUP LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |