Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 19/20 | 0.80 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216414 | 0.94 | ALOX5AP (0.78) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9146019 | 0.92 | ALOX5AP (0.81) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL13920496 | 0.92 | ALOX5AP (0.83) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9218603 | 0.89 | ALOX5AP (0.79) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| Quiflapon SCHEMBL30505315 | 0.89 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| Quiflapon SCHEMBL502947 | 0.89 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| Quiflapon SCHEMBL29370879 | 0.89 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| Quiflapon SCHEMBL29372303 | 0.89 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9148924 | 0.89 | ALOX5AP (0.80) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| Quiflapon SCHEMBL9306864 | 0.89 | ALOX5AP (0.98) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399699-A | Lipoxygenase inihibitors, antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-03-21 | — | — | US | disclosed |