SCHEMBL9150313

SCHEMBL9150313

Cc1ccsc1C(=O)NC1CCCCC1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.73
NPC1 O15118 6/20 0.73
ALPL P05186 1/20 0.73
ALPI P09923 1/20 0.73
ALPG P10696 1/20 0.73
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 3/20 0.56
CYP1A2 P05177 3/20 0.55
MEN1 O00255 2/20 0.55
CYP3A4 P08684 2/20 0.55
KMT2A Q03164 2/20 0.55
GSK3B P49841 2/20 0.55
GAA P10253 1/20 0.55
CYP2C9 P11712 1/20 0.55
GSK3A P49840 1/20 0.55
HPGD P15428 4/20 0.55
CYP2C19 P33261 2/20 0.55
TSHR P16473 2/20 0.55
CYP2D6 P10635 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3455705 1.00 RAB9A (0.73) RAB9ANPC1ALPLALPIALPG
SCHEMBL13162015 0.85 NPC1 (0.55) RAB9ANPC1ALPLALPIALPG
SCHEMBL2075958 0.79 NPC1 (0.55) RAB9ANPC1ALPLALPIALPG
SCHEMBL32690627 0.79 AXL (0.56) RAB9ANPC1ALPLALPIALPG
SCHEMBL27753306 0.76 NPC1 (0.52) RAB9ANPC1ALPLALPIALPG
SCHEMBL9412184 0.75 RAB9A (0.52) RAB9ANPC1ALPLALPIALPG
SCHEMBL12160921 0.73 NPC1 (0.46) RAB9ANPC1ALPLALPIALPG
SCHEMBL7983727 0.72 GAA (0.67) RAB9ANPC1KDM4EALDH1A1KMT2A
SCHEMBL13753386 0.71 SMN1; SMN2 (0.55) RAB9ANPC1ALDH1A1GSK3BGAA
SCHEMBL8198182 0.71 NPC1 (1.00) RAB9ANPC1KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416103-A N-cyclohex(en)yl-pyridine carboxamides and compositions containing them for controlling fungal pests BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed