Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156919 | 0.99 | OXER1 (0.56) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9154226 | 0.96 | OXER1 (0.55) | OXER1HTR6HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL9156117 | 0.94 | OXER1 (0.54) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9149567 | 0.91 | OXER1 (0.48) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9153676 | 0.84 | AKR1C3 (0.50) | ELANEKMT2AL3MBTL1DYRK1APBRM1 | |
| SCHEMBL5444461 | 0.84 | OXER1 (0.64) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9368697 | 0.83 | OXER1 (0.56) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9156549 | 0.83 | AKR1C3 (0.46) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL9154277 | 0.83 | OXER1 (0.55) | OXER1HTR6HTR1AHTR1DHTR1B | |
| SCHEMBL10696303 | 0.78 | OXER1 (0.56) | OXER1HTR6HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| CN-1054250-A | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-09-04 | — | — | CN | disclosed |