Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149567 | 0.88 | OXER1 (0.48) | AKR1C3AKR1C2ELANEALDH1A1PBRM1 | |
| SCHEMBL9154226 | 0.86 | OXER1 (0.55) | ELANEALDH1A1PBRM1KMT2AL3MBTL1 | |
| SCHEMBL27474952 | 0.85 | AKR1C3 (0.59) | AKR1C3AKR1C2ELANEALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9156117 | 0.85 | OXER1 (0.54) | ELANEALDH1A1PBRM1KMT2AL3MBTL1 | |
| SCHEMBL9156919 | 0.85 | OXER1 (0.56) | ELANEALDH1A1PBRM1KMT2AL3MBTL1 | |
| SCHEMBL9150530 | 0.84 | OXER1 (0.58) | ELANEPBRM1KMT2AL3MBTL1DYRK1A | |
| SCHEMBL4216463 | 0.80 | AKR1C3 (0.58) | AKR1C3AKR1C2ALDH1A1LMNAAKR1C4 | |
| SCHEMBL13802421 | 0.78 | KMT2A (0.57) | AKR1C3AKR1C2ALDH1A1LMNAAKR1C4 | |
| SCHEMBL12479702 | 0.77 | CDC25A (0.51) | ALDH1A1LMNAL3MBTL1CDC25AKDM4E | |
| SCHEMBL2467334 | 0.76 | CDC25A (0.54) | AKR1C3AKR1C2ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516849-B1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516849-A1 | INDOLE DERIVATIVES. | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | EP | disclosed |
| WO-1991013060-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| CN-1054250-A | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-09-04 | — | — | CN | disclosed |