SCHEMBL9150540

SCHEMBL9150540

O=C(Nc1cccc(O)c1C(=O)O)OCCCl

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
CA14 Q9ULX7 3/20 0.44
PLK1 P53350 1/20 0.43
PLK3 Q9H4B4 1/20 0.43
ALDH1A1 P00352 2/20 0.40
LPAR2 Q9HBW0 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655078 0.86 PLK1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL8653008 0.83 SMN1; SMN2 (0.56) PLK1PLK3ALDH1A1NPC1RAB9A
SCHEMBL8657531 0.82 ALDH1A1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8652836 0.82 PLK1 (0.57) PLK1PLK3ALDH1A1NPC1RAB9A
SCHEMBL9145624 0.82 NPC1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9151043 0.82 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL8652584 0.82 PLK1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL8655980 0.81 PLK1 (0.59) PLK1PLK3ALDH1A1NPC1RAB9A
SCHEMBL8658169 0.81 PLK1 (0.59) PLK1PLK3ALDH1A1NPC1RAB9A
SCHEMBL8655100 0.81 PLK1 (0.59) PLK1PLK3ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476957-A Dye for heat sensitive recording MITSUI TOATSU CHEMICALS, INC. (JP) 1995-12-19 US disclosed