Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146617 | 0.90 | MEN1 (0.38) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9144401 | 0.89 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9147836 | 0.88 | MEN1 (0.39) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9735138 | 0.88 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9144578 | 0.86 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9147881 | 0.86 | NR1H4 (0.39) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9146528 | 0.86 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9147849 | 0.85 | NR1H4 (0.41) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9146536 | 0.85 | USP2 (0.41) | KMT2AMEN1RAB9ANR1H4NCOA1 | |
| SCHEMBL9146329 | 0.85 | MEN1 (0.36) | KMT2AMEN1RAB9ANR1H4NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447943-A | Smooth muscle relaxants or bronchodilators | SYNTEX (U.S.A.) INC. (US) | 1995-09-05 | — | — | US | disclosed |
| US-5250547-A | Potassium channel activators; 5-lipoxygenase inhibitors; muscle relaxants; bronchodilators | SYNTEX (U.S.A.) INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0529654-A1 | Benzopyran derivatives as potassium channel activators and 5-lipoxygenase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1993-03-03 | — | — | EP | disclosed |